node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ELI_00130 | ELI_06415 | ELI_00130 | ELI_06415 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | 0.951 |
ELI_00130 | ELI_10290 | ELI_00130 | ELI_10290 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | Chorismate mutase/prephenate dehydratase; COG0077 Prephenate dehydratase. | 0.936 |
ELI_00130 | ELI_11420 | ELI_00130 | ELI_11420 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | Putative cyclohexadienyl dehydrogenase; COG0287 Prephenate dehydrogenase. | 0.918 |
ELI_00130 | hisC | ELI_00130 | ELI_11415 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.926 |
ELI_06415 | ELI_00130 | ELI_06415 | ELI_00130 | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.951 |
ELI_06415 | hisC | ELI_06415 | ELI_11415 | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.918 |
ELI_10290 | ELI_00130 | ELI_10290 | ELI_00130 | Chorismate mutase/prephenate dehydratase; COG0077 Prephenate dehydratase. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.936 |
ELI_10290 | ELI_11420 | ELI_10290 | ELI_11420 | Chorismate mutase/prephenate dehydratase; COG0077 Prephenate dehydratase. | Putative cyclohexadienyl dehydrogenase; COG0287 Prephenate dehydrogenase. | 0.953 |
ELI_10290 | hisC | ELI_10290 | ELI_11415 | Chorismate mutase/prephenate dehydratase; COG0077 Prephenate dehydratase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.938 |
ELI_11420 | ELI_00130 | ELI_11420 | ELI_00130 | Putative cyclohexadienyl dehydrogenase; COG0287 Prephenate dehydrogenase. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.918 |
ELI_11420 | ELI_10290 | ELI_11420 | ELI_10290 | Putative cyclohexadienyl dehydrogenase; COG0287 Prephenate dehydrogenase. | Chorismate mutase/prephenate dehydratase; COG0077 Prephenate dehydratase. | 0.953 |
ELI_11420 | hisC | ELI_11420 | ELI_11415 | Putative cyclohexadienyl dehydrogenase; COG0287 Prephenate dehydrogenase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.996 |
ELI_13805 | hisC | ELI_13805 | ELI_11415 | COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.919 |
ELI_13805 | hisD | ELI_13805 | ELI_02595 | COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.909 |
hisA | hisB | ELI_09560 | ELI_09570 | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.996 |
hisA | hisC | ELI_09560 | ELI_11415 | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.941 |
hisA | hisD | ELI_09560 | ELI_02595 | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.991 |
hisA | hisG | ELI_09560 | ELI_02600 | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.975 |
hisA | hisI | ELI_09560 | ELI_05885 | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.999 |
hisB | hisA | ELI_09570 | ELI_09560 | COG0131 Imidazoleglycerol-phosphate dehydratase. | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | 0.996 |