STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR52277.1Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. (320 aa)    
Predicted Functional Partners:
EAR50659.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
 
 0.998
EAR52279.1
metF protein-like; COG0685 5,10-methylenetetrahydrofolate reductase.
 
 
 0.996
EAR50661.1
Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein.
 
 0.996
EAR50084.1
COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.980
EAR52280.1
Hypothetical protein.
 
     0.953
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.913
fhs
Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.912
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.912
EAR50689.1
COG0460 Homoserine dehydrogenase.
  
 
 0.905
EAR49560.1
COG3894 Uncharacterized metal-binding protein.
 
 
 
 0.896
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.