STRINGSTRING
yacG protein (Pelagibaca bermudensis) - STRING interaction network
"yacG" - DNA gyrase inhibitor YacG in Pelagibaca bermudensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yacGDNA gyrase inhibitor YacG ; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (62 aa)    
Predicted Functional Partners:
R2601_09320
Ribonuclease, Rne/Rng family protein (283 aa)
              0.914
R2601_09310
NifS-related protein (416 aa)
              0.859
R2601_09355
UPF0262 protein R2601_09355 (159 aa)
 
          0.680
R2601_09350
Arsenate reductase (148 aa)
 
          0.667
infA
Translation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)
 
          0.664
R2601_21977
Uncharacterized protein (235 aa)
   
          0.560
R2601_09365
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (433 aa)
 
          0.515
R2601_01240
Transcriptional regulatory protein (231 aa)
   
          0.512
R2601_09375
Uncharacterized protein (154 aa)
 
          0.466
R2601_14680
Maf-like protein R2601_14680 (199 aa)
              0.451
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
Server load: low (6%) [HD]