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glyA protein (Pelagibaca bermudensis) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Pelagibaca bermudensis
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
glyASerine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (431 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (aminomethyl-transferring) ; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (948 aa)
   
 
  0.993
R2601_11439
Phosphoserine phosphatase (289 aa)
   
  0.990
R2601_13249
FolC bifunctional protein (425 aa)
   
  0.988
R2601_15265
Aminomethyltransferase ; The glycine cleavage system catalyzes the degradation of glycine (375 aa)
 
  0.987
purH
Bifunctional purine biosynthesis protein PurH (529 aa)
   
  0.984
R2601_18690
Sarcosine oxidase alpha subunit (996 aa)
   
  0.982
R2601_10189
Sarcosine oxidase, alpha subunit family protein (1012 aa)
   
  0.982
R2601_01365
Serine--glyoxylate transaminase, putative (395 aa)
   
 
  0.981
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (300 aa)
 
  0.976
R2601_18668
Putative sarcosine dehydrogenase protein (853 aa)
   
  0.974
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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