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nrdR protein (Pelagibaca bermudensis) - STRING interaction network
"nrdR" - Transcriptional repressor NrdR in Pelagibaca bermudensis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
nrdRTranscriptional repressor NrdR ; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (156 aa)    
Predicted Functional Partners:
R2601_10414
Riboflavin biosynthesis protein RibD ; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate (350 aa)
   
 
  0.947
lexA
LexA repressor ; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (231 aa)
 
   
  0.645
R2601_16870
Nucleotide-binding protein R2601_16870 ; Displays ATPase and GTPase activities (308 aa)
 
          0.607
R2601_15447
DNA polymerase I (935 aa)
         
  0.554
R2601_07781
6,7-dimethyl-8-ribityllumazine synthase ; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (183 aa)
   
   
  0.554
R2601_07703
AAA ATPase (434 aa)
 
        0.553
R2601_21281
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (437 aa)
   
   
  0.545
R2601_09365
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (433 aa)
   
   
  0.545
R2601_00895
6,7-dimethyl-8-ribityllumazine synthase ; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (158 aa)
   
   
  0.536
R2601_18633
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (707 aa)
         
  0.535
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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