Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
4’-phosphopantetheinyl transferase AcpS ; Transfers the 4’-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (134 aa)
Predicted Functional Partners:
Malonyl CoA-acyl carrier protein transacylase (313 aa)
Acyl carrier protein ; Carrier of the growing fatty acid chain in fatty acid biosynthesis (77 aa)
Uncharacterized protein (343 aa)
MaoC-related acyl dehydratase (152 aa)
Uncharacterized protein (287 aa)
MaoC domain protein (151 aa)
Putative acyl dehydratase (144 aa)
Putative monoamine oxidase regulatory protein (147 aa)
Pyridoxine 5’-phosphate synthase ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5’-phosphate (PNP) and inorganic phosphate (250 aa)