STRINGSTRING
R2601_13940 protein (Pelagibaca bermudensis) - STRING interaction network
"R2601_13940" - O-6-methylguanine-DNA-alkyltransferase in Pelagibaca bermudensis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
R2601_13940O-6-methylguanine-DNA-alkyltransferase ; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (169 aa)    
Predicted Functional Partners:
R2601_13935
Transcriptional regulatory protein (186 aa)
 
  0.995
R2601_23795
Phospholipase/carboxylesterase family protein (430 aa)
 
 
  0.858
queG
Queuosine biosynthesis protein QueG ; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (344 aa)
       
  0.775
R2601_15447
DNA polymerase I (935 aa)
     
 
  0.692
nth
DNA-(apurinic or apyrimidinic site) lyase ; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (214 aa)
 
     
  0.656
plsY
Lysophosphatidic acid synthase ; Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (205 aa)
              0.650
rpoD
Sigma-70 ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (661 aa)
     
 
  0.648
R2601_13925
Dihydroorotase (427 aa)
              0.632
R2601_13945
Uncharacterized protein (48 aa)
              0.606
R2601_14080
Alkylated DNA repair protein, putative (201 aa)
   
   
  0.562
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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