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R2601_14420 protein (Pelagibaca bermudensis) - STRING interaction network
"R2601_14420" - DNA polymerase III subunit beta in Pelagibaca bermudensis
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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R2601_14420DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (372 aa)    
Predicted Functional Partners:
R2601_15447
DNA polymerase I (935 aa)
   
  0.998
R2601_10369
DNA-directed DNA polymerase (1174 aa)
   
  0.996
R2601_17304
DNA polymerase III subunits gamma and tau (588 aa)
 
  0.996
gyrB
DNA gyrase subunit B ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (805 aa)
  0.994
R2601_19599
DNA polymerase III subunit delta (372 aa)
 
  0.993
dnaA
Chromosomal replication initiator protein DnaA ; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (451 aa)
 
 
  0.990
R2601_14665
Putative DNA polymerase III, epsilon subunit and related 3’-5’ exonuclease (229 aa)
 
 
  0.989
R2601_18633
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (707 aa)
     
 
  0.988
R2601_10309
Ribonucleoside-diphosphate reductase, putative (762 aa)
     
 
  0.988
R2601_18628
Ribonucleoside-diphosphate reductase subunit beta ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (326 aa)
     
 
  0.988
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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