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nth protein (Pelagibaca bermudensis) - STRING interaction network
"nth" - DNA-(apurinic or apyrimidinic site) lyase in Pelagibaca bermudensis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nthDNA-(apurinic or apyrimidinic site) lyase ; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (214 aa)    
Predicted Functional Partners:
R2601_22542
Exodeoxyribonuclease III (260 aa)
 
 
  0.947
R2601_15457
Kinase, pfkB family protein (337 aa)
              0.887
der
GTP-binding protein EngA ; GTPase that plays an essential role in the late steps of ribosome biogenesis (487 aa)
   
   
  0.836
R2601_11074
Exodeoxyribonuclease III, putative (262 aa)
     
  0.830
R2601_15447
DNA polymerase I (935 aa)
   
 
  0.773
R2601_11004
Polyribonucleotide nucleotidyltransferase (463 aa)
 
   
  0.722
R2601_15472
ADA regulatory protein (278 aa)
         
  0.715
R2601_13940
O-6-methylguanine-DNA-alkyltransferase ; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (169 aa)
 
     
  0.656
eno
2-phosphoglycerate dehydratase ; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (424 aa)
 
     
  0.638
R2601_11831
Dihydropyrimidine dehydrogenase (434 aa)
         
  0.607
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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