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R2601_18700 protein (Pelagibaca bermudensis) - STRING interaction network
"R2601_18700" - L-serine ammonia-lyase in Pelagibaca bermudensis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
R2601_18700L-serine ammonia-lyase (469 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (431 aa)
   
 
  0.896
R2601_18690
Sarcosine oxidase alpha subunit (996 aa)
 
 
  0.878
R2601_18685
Sarcosine oxidase delta subunit (102 aa)
 
     
  0.826
R2601_18705
Formyl-FH(4) hydrolase ; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (294 aa)
         
  0.821
R2601_11034
Threonine dehydratase (323 aa)
   
 
  0.819
R2601_01360
Pyridoxal-phosphate dependent enzyme (321 aa)
   
 
  0.819
R2601_26746
Probable threonine dehydratase protein (338 aa)
       
  0.819
ilvA
Threonine deaminase ; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (414 aa)
       
  0.819
R2601_13699
Threonine dehydratase (305 aa)
       
  0.794
R2601_11439
Phosphoserine phosphatase (289 aa)
         
  0.791
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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