STRINGSTRING
coaX protein (Pelagibaca bermudensis) - STRING interaction network
"coaX" - Pantothenic acid kinase in Pelagibaca bermudensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXPantothenic acid kinase ; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (259 aa)    
Predicted Functional Partners:
panC
Pantoate-activating enzyme ; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (280 aa)
   
 
  0.988
R2601_21872
Biotin--acetyl-CoA-carboxylase ligase (248 aa)
 
   
  0.898
R2601_21882
Metallo-beta-lactamase family protein (555 aa)
              0.887
R2601_09937
Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase (398 aa)
   
 
  0.879
coaD
Pantetheine-phosphate adenylyltransferase ; Reversibly transfers an adenylyl group from ATP to 4’- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (165 aa)
   
   
  0.867
eno
2-phosphoglycerate dehydratase ; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (424 aa)
     
      0.724
nuoN
NDH-1 subunit N ; NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (480 aa)
              0.713
R2601_21862
NADH dehydrogenase subunit M (516 aa)
              0.706
R2601_21887
DNA binding protein, putative (189 aa)
              0.689
R2601_24734
Nicotinamide nucleotide repair protein ; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (536 aa)
 
          0.598
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
Server load: low (11%) [HD]