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R2601_22062 protein (Pelagibaca bermudensis) - STRING interaction network
"R2601_22062" - Probable ClpA/B-type protease in Pelagibaca bermudensis
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R2601_22062Probable ClpA/B-type protease (914 aa)    
Predicted Functional Partners:
R2601_22077
Uncharacterized protein (502 aa)
 
 
  0.967
R2601_16100
Uncharacterized protein (503 aa)
 
 
  0.944
dnaJ
Chaperone protein DnaJ ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (385 aa)
   
  0.933
dnaK
Heat shock protein 70 ; Acts as a chaperone (642 aa)
 
 
  0.928
clpS
ATP-dependent Clp protease adapter protein ClpS ; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (120 aa)
   
 
  0.921
R2601_22072
Uncharacterized protein (179 aa)
 
   
  0.920
R2601_22092
Uncharacterized protein (625 aa)
 
   
  0.917
R2601_22097
Uncharacterized protein (354 aa)
 
   
  0.913
R2601_22122
Uncharacterized protein (1184 aa)
 
   
  0.905
grpE
HSP-70 cofactor ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depend [...] (185 aa)
   
 
  0.901
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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