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glmU protein (Pelagibaca bermudensis) - STRING interaction network
"glmU" - Bifunctional protein GlmU in Pelagibaca bermudensis
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glmUBifunctional protein GlmU ; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (449 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase ; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (447 aa)
 
  0.999
glmS
L-glutamine--D-fructose-6-phosphate amidotransferase ; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (605 aa)
 
  0.994
prs
Phosphoribosyl pyrophosphate synthase ; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (336 aa)
   
  0.964
murA
UDP-N-acetylglucosamine enolpyruvyl transferase ; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (423 aa)
 
  0.941
purF
Glutamine phosphoribosylpyrophosphate amidotransferase ; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (488 aa)
     
   
  0.824
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase ; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (262 aa)
   
 
  0.822
murC
UDP-N-acetylmuramoyl-L-alanine synthetase ; Cell wall formation (478 aa)
 
 
  0.817
R2601_22322
Phosphoglycolate phosphatase (220 aa)
              0.787
R2601_14960
Uncharacterized protein (325 aa)
     
 
    0.785
R2601_13689
Nucleotide sugar epimerase/dehydratase (628 aa)
       
    0.784
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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