STRINGSTRING
proA protein (Pelagibaca bermudensis) - STRING interaction network
"proA" - Glutamyl-gamma-semialdehyde dehydrogenase in Pelagibaca bermudensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamyl-gamma-semialdehyde dehydrogenase ; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate (421 aa)    
Predicted Functional Partners:
proB
Gamma-glutamyl kinase ; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate (368 aa)
 
  0.999
R2601_12990
Glutamate synthase, large subunit (1537 aa)
     
 
  0.966
R2601_23338
Uncharacterized protein (198 aa)
         
    0.936
proC
PCA reductase ; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline (271 aa)
 
   
  0.932
argD
Acetylornithine aminotransferase (398 aa)
   
  0.886
R2601_18985
Bifunctional protein PutA ; Oxidizes proline to glutamate for use as a carbon and nitrogen source (1142 aa)
   
 
  0.862
R2601_24724
Glutamine synthetase (468 aa)
   
 
  0.834
R2601_07941
Glutamine synthetase III (438 aa)
   
 
  0.834
obg
GTP-binding protein Obg ; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control (343 aa)
       
  0.825
recA
Protein RecA ; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (213 aa)
     
   
  0.824
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
Server load: low (6%) [HD]