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prfA protein (Pelagibaca bermudensis) - STRING interaction network
"prfA" - Peptide chain release factor 1 in Pelagibaca bermudensis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prfAPeptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (349 aa)    
Predicted Functional Partners:
prmC
Protein-glutamine N-methyltransferase PrmC ; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif (282 aa)
 
  0.998
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (152 aa)
 
 
  0.907
lepA
Ribosomal back-translocase LepA ; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (600 aa)
 
   
  0.892
frr
Ribosome-releasing factor ; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (187 aa)
 
 
  0.883
rpsP
30S ribosomal protein S16 (124 aa)
 
 
  0.873
rplQ
50S ribosomal protein L17 (139 aa)
 
 
  0.868
rplO
50S ribosomal protein L15 ; Binds to the 23S rRNA (156 aa)
 
 
  0.868
mnmE
tRNA modification GTPase MnmE ; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (373 aa)
 
   
  0.867
rplP
50S ribosomal protein L16 ; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (137 aa)
 
 
  0.856
pth
Peptidyl-tRNA hydrolase ; The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (241 aa)
 
   
  0.850
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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