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ispDF protein (Pelagibaca bermudensis) - STRING interaction network
"ispDF" - Bifunctional enzyme IspD/IspF in Pelagibaca bermudensis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ispDFBifunctional enzyme IspD/IspF ; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (378 aa)    
Predicted Functional Partners:
dxr
2-C-methyl-D-erythritol 4-phosphate synthase ; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (390 aa)
 
  0.997
ispE
4-(cytidine-5’-diphospho)-2-C-methyl-D-erythritol kinase ; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (293 aa)
 
 
  0.992
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase ; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (377 aa)
 
 
  0.984
R2601_26281
Putative competence-damaged inducible protein (159 aa)
 
   
  0.954
R2601_26276
Phosphatidylglycerolphosphate phosphatase A ; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (161 aa)
         
  0.934
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase ; Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (315 aa)
 
   
  0.934
trmD
tRNA [GM37] methyltransferase ; Specifically methylates guanosine-37 in various tRNAs (271 aa)
   
  0.909
dxs
1-deoxyxylulose-5-phosphate synthase ; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (641 aa)
 
   
  0.898
murC
UDP-N-acetylmuramoyl-L-alanine synthetase ; Cell wall formation (478 aa)
     
 
  0.892
R2601_15447
DNA polymerase I (935 aa)
   
   
  0.846
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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