node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carB | purC | RB2654_10498 | RB2654_02070 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.404 |
carB | purD | RB2654_10498 | RB2654_08067 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.849 |
carB | purE | RB2654_10498 | RB2654_19183 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.783 |
carB | purF | RB2654_10498 | RB2654_02259 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.982 |
carB | purH | RB2654_10498 | RB2654_12154 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.723 |
carB | purL | RB2654_10498 | RB2654_02494 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.760 |
carB | purM | RB2654_10498 | RB2654_01990 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.569 |
carB | purN | RB2654_10498 | RB2654_01995 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.663 |
carB | purQ | RB2654_10498 | RB2654_02090 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.925 |
purC | carB | RB2654_02070 | RB2654_10498 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.404 |
purC | purD | RB2654_02070 | RB2654_08067 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.992 |
purC | purE | RB2654_02070 | RB2654_19183 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purC | purF | RB2654_02070 | RB2654_02259 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.994 |
purC | purH | RB2654_02070 | RB2654_12154 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.992 |
purC | purL | RB2654_02070 | RB2654_02494 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.988 |
purC | purM | RB2654_02070 | RB2654_01990 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.991 |
purC | purN | RB2654_02070 | RB2654_01995 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.989 |
purC | purQ | RB2654_02070 | RB2654_02090 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.992 |
purC | purS | RB2654_02070 | RB2654_02075 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.991 |
purD | carB | RB2654_08067 | RB2654_10498 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.849 |