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ndk protein (Maritimibacter alkaliphilus) - STRING interaction network
"ndk" - Nucleoside-2-P kinase in Maritimibacter alkaliphilus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ndkNucleoside-2-P kinase ; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (140 aa)    
Predicted Functional Partners:
pyrG
UTP--ammonia ligase ; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (547 aa)
 
 
  0.988
RB2654_13549
Nucleoside-triphosphate pyrophosphatase ; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (204 aa)
   
    0.986
cmk
Cytidine monophosphate kinase (203 aa)
   
 
  0.986
gmk
GMP kinase ; Essential for recycling GMP and indirectly, cGMP (213 aa)
   
  0.986
RB2654_04169
Uridylate kinase ; Catalyzes the reversible phosphorylation of UMP to UDP (254 aa)
   
 
  0.986
tmk
dTMP kinase ; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (207 aa)
   
 
  0.986
RB2654_16236
RelA/SpoT family protein ; In eubacteria ppGpp (guanosine 3’-diphosphate 5-’ diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (707 aa)
   
 
  0.985
RB2654_08882
Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (156 aa)
   
 
    0.984
RB2654_04361
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent (1230 aa)
   
 
  0.984
rpoB
Transcriptase subunit beta ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1380 aa)
   
  0.904
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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