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nth protein (Maritimibacter alkaliphilus) - STRING interaction network
"nth" - DNA-(apurinic or apyrimidinic site) lyase in Maritimibacter alkaliphilus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nthDNA-(apurinic or apyrimidinic site) lyase ; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (210 aa)    
Predicted Functional Partners:
RB2654_03144
Exodeoxyribonuclease III (267 aa)
 
 
  0.953
RB2654_10369
Kinase, pfkB family protein (329 aa)
              0.913
RB2654_15589
Exodeoxyribonuclease III, putative (262 aa)
 
 
  0.894
der
GTP-binding protein EngA ; GTPase that plays an essential role in the late steps of ribosome biogenesis (481 aa)
   
   
  0.879
RB2654_10393
DNA polymerase I (932 aa)
   
 
  0.770
RB2654_10354
ADA regulatory protein (289 aa)
         
  0.739
pnp
Polynucleotide phosphorylase ; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (716 aa)
 
   
  0.711
RB2654_18968
O-6-methylguanine-DNA-alkyltransferase ; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (150 aa)
 
     
  0.667
RB2654_10359
Uncharacterized protein (211 aa)
              0.619
mutL
DNA mismatch repair protein MutL ; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (610 aa)
 
 
  0.605
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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