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RB2654_11523 protein (Maritimibacter alkaliphilus) - STRING interaction network
"RB2654_11523" - FolC bifunctional protein in Maritimibacter alkaliphilus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
RB2654_11523FolC bifunctional protein (423 aa)    
Predicted Functional Partners:
RB2654_19783
Dihydropteroate pyrophosphorylase ; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (321 aa)
 
  0.999
RB2654_05942
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (159 aa)
   
  0.990
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (430 aa)
   
  0.950
fhs
Formyltetrahydrofolate synthetase (558 aa)
   
 
  0.948
RB2654_19928
L-threonine aldolase, low-specificity, putative (350 aa)
       
    0.917
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta ; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (333 aa)
   
        0.897
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (272 aa)
     
 
  0.871
RB2654_16246
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (168 aa)
 
 
  0.821
RB2654_11513
Uncharacterized protein (304 aa)
   
        0.789
truA
tRNA-uridine isomerase I ; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (257 aa)
 
   
  0.729
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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