STRINGSTRING
tsaD protein (Maritimibacter alkaliphilus) - STRING interaction network
"tsaD" - tRNA threonylcarbamoyladenosine biosynthesis protein TsaD in Maritimibacter alkaliphilus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDtRNA threonylcarbamoyladenosine biosynthesis protein TsaD ; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (365 aa)    
Predicted Functional Partners:
RB2654_18618
Uncharacterized protein (180 aa)
 
 
0.915
RB2654_13700
Uncharacterized protein (162 aa)
   
  0.905
secA
Protein translocase subunit SecA ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (899 aa)
   
  0.857
pheT
Phenylalanyl-tRNA synthetase beta subunit (808 aa)
 
   
  0.853
ksgA
S-adenosylmethionine-6-N’, N’-adenosyl(rRNA) dimethyltransferase ; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (280 aa)
 
   
  0.834
crcB
Putative fluoride ion transporter CrcB ; Important for reducing fluoride concentration in the cell, thus reducing its toxicity (125 aa)
     
      0.806
RB2654_13059
Glycerol-3-phosphate dehydrogenase (296 aa)
   
   
  0.798
RB2654_13069
Uroporphyrinogen-III synthase, putative (221 aa)
 
          0.777
RB2654_19618
Elongation factor P (187 aa)
 
   
  0.776
RB2654_10393
DNA polymerase I (932 aa)
 
   
  0.773
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
Server load: low (6%) [HD]