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smpB protein (Maritimibacter alkaliphilus) - STRING interaction network
"smpB" - Small protein B in Maritimibacter alkaliphilus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
smpBSmall protein B ; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a "tag peptide", a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tra [...] (161 aa)    
Predicted Functional Partners:
rplS
50S ribosomal protein L19 ; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (126 aa)
 
   
  0.979
rpsB
30S ribosomal protein S2 (228 aa)
 
 
  0.968
frr
Ribosome-releasing factor ; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (188 aa)
 
   
  0.952
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (235 aa)
 
 
  0.946
rplT
50S ribosomal protein L20 ; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (120 aa)
   
     
  0.934
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (154 aa)
 
 
 
  0.930
rplF
50S ribosomal protein L6 ; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (177 aa)
 
 
 
  0.926
rplP
50S ribosomal protein L16 ; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (137 aa)
 
     
  0.921
rpsM
30S ribosomal protein S13 ; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (116 aa)
 
     
  0.916
rpmA
50S ribosomal protein L27 (89 aa)
 
     
  0.909
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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