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hisG protein (Maritimibacter alkaliphilus) - STRING interaction network
"hisG" - ATP phosphoribosyltransferase in Maritimibacter alkaliphilus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisGATP phosphoribosyltransferase ; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (232 aa)    
Predicted Functional Partners:
RB2654_18933
ATP phosphoribosyltransferase regulatory subunit (364 aa)
 
 
  0.997
hisE
Phosphoribosyl-ATP pyrophosphatase (102 aa)
   
 
  0.996
RB2654_18928
Histidyl-tRNA synthetase (517 aa)
 
  0.993
hisI
Phosphoribosyl-AMP cyclohydrolase ; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (119 aa)
 
 
  0.989
hisF
ImGP synthase subunit HisF ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (253 aa)
 
  0.978
RB2654_20078
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (434 aa)
 
 
  0.977
RB2654_10788
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (442 aa)
 
 
  0.971
hisH
ImGP synthase subunit HisH ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (211 aa)
 
   
  0.927
hisB
Imidazoleglycerol-phosphate dehydratase (195 aa)
 
   
  0.920
hisC
Imidazole acetol-phosphate transaminase (367 aa)
 
   
  0.883
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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