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RB2654_18968 protein (Maritimibacter alkaliphilus) - STRING interaction network
"RB2654_18968" - O-6-methylguanine-DNA-alkyltransferase in Maritimibacter alkaliphilus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RB2654_18968O-6-methylguanine-DNA-alkyltransferase ; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (150 aa)    
Predicted Functional Partners:
RB2654_01790
DNA-3-methyladenine glycosylase II, putative (210 aa)
 
 
  0.947
RB2654_16016
DNA-3-methyladenine glycosylase I (184 aa)
       
  0.875
ileS
Isoleucyl-tRNA synthetase ; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (996 aa)
              0.865
queG
Queuosine biosynthesis protein QueG ; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (344 aa)
       
  0.782
rpoD
Sigma-70 ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (670 aa)
     
 
  0.762
RB2654_10393
DNA polymerase I (932 aa)
     
 
  0.686
nth
DNA-(apurinic or apyrimidinic site) lyase ; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (210 aa)
 
     
  0.667
RB2654_04224
Tyrosine recombinase XerC (315 aa)
 
 
 
  0.566
rpoH
RNA polymerase sigma-32 factor (298 aa)
     
 
  0.562
RB2654_18943
Putative MrcB penicillin binding protein B (727 aa)
              0.561
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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