STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAS47401.1COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase. (418 aa)    
Predicted Functional Partners:
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.921
ilvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
     
 0.920
EAS47386.1
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
     
 0.885
EAS47439.1
4-amino-4-deoxychorismate lyase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
     
 0.525
EAS46368.1
D-amino acid aminotransferase, putative; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
     
 0.469
EAS47398.1
COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.465
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.465
EAS47400.1
Oxidoreductase, 2OG-Fe(II) oxygenase family protein; COG3145 Alkylated DNA repair protein.
       0.465
EAS46525.1
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
   
 0.441
Your Current Organism:
gamma proteobacterium HTCC2207
NCBI taxonomy Id: 314287
Other names: g. proteobacterium HTCC2207, marine gamma proteobacterium HTCC2207
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