node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CcpA | fruA | LCA_0415 | LCA_1050 | CcpA transcriptional regulator (Catabolic control protein A). | Fructose-specific phosphotransferase system, enzyme IIABC. | 0.495 |
CcpA | hprK | LCA_0415 | LCA_0516 | CcpA transcriptional regulator (Catabolic control protein A). | Hpr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.717 |
CcpA | ptsH | LCA_0415 | LCA_1463 | CcpA transcriptional regulator (Catabolic control protein A). | Phosphocarrier protein HPr (Histidine-containing protein). | 0.829 |
CcpA | ptsI | LCA_0415 | LCA_1462 | CcpA transcriptional regulator (Catabolic control protein A). | Phosphoenolpyruvate-protein phosphotransferase(Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.564 |
LCA_0515 | gps | LCA_0515 | LCA_0518 | Hypothetical integral membrane protein. | [NAD(P)+]-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.698 |
LCA_0515 | hprK | LCA_0515 | LCA_0516 | Hypothetical integral membrane protein. | Hpr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.739 |
LCA_0515 | lgt | LCA_0515 | LCA_0517 | Hypothetical integral membrane protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.743 |
LCA_0515 | trxB2 | LCA_0515 | LCA_0520 | Hypothetical integral membrane protein. | Thioredoxin reductase. | 0.524 |
LCA_0692 | fruA | LCA_0692 | LCA_1050 | Putative serine/threonine protein kinase. | Fructose-specific phosphotransferase system, enzyme IIABC. | 0.528 |
LCA_0692 | hprK | LCA_0692 | LCA_0516 | Putative serine/threonine protein kinase. | Hpr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.692 |
LCA_0692 | lgt | LCA_0692 | LCA_0517 | Putative serine/threonine protein kinase. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.439 |
fruA | CcpA | LCA_1050 | LCA_0415 | Fructose-specific phosphotransferase system, enzyme IIABC. | CcpA transcriptional regulator (Catabolic control protein A). | 0.495 |
fruA | LCA_0692 | LCA_1050 | LCA_0692 | Fructose-specific phosphotransferase system, enzyme IIABC. | Putative serine/threonine protein kinase. | 0.528 |
fruA | hprK | LCA_1050 | LCA_0516 | Fructose-specific phosphotransferase system, enzyme IIABC. | Hpr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.763 |
fruA | manL | LCA_1050 | LCA_0449 | Fructose-specific phosphotransferase system, enzyme IIABC. | Mannose-specific phosphotransferase system, enzyme IIAB. | 0.843 |
fruA | ptsH | LCA_1050 | LCA_1463 | Fructose-specific phosphotransferase system, enzyme IIABC. | Phosphocarrier protein HPr (Histidine-containing protein). | 0.996 |
fruA | ptsI | LCA_1050 | LCA_1462 | Fructose-specific phosphotransferase system, enzyme IIABC. | Phosphoenolpyruvate-protein phosphotransferase(Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.988 |
gps | LCA_0515 | LCA_0518 | LCA_0515 | [NAD(P)+]-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Hypothetical integral membrane protein. | 0.698 |
gps | hprK | LCA_0518 | LCA_0516 | [NAD(P)+]-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Hpr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.819 |
gps | lgt | LCA_0518 | LCA_0517 | [NAD(P)+]-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.937 |