STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prtMProtein maturation protease precursor (peptidylprolyl isomerase); Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (303 aa)    
Predicted Functional Partners:
pepQ
Xaa-Pro dipeptidase (Proline dipeptidase).
     
 0.711
LCA_0628
Putative diadenosine polyphosphate hydrolase.
  
 
 0.707
pepM
Methionyl aminopeptidase M; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
     
 0.701
pepR
Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
 
 0.632
LCA_0436
Putative peptidylprolyl isomerase (Peptidylprolyl cis-trans isomerase) (PPIase); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.621
nusA
Transcription elongation protein NusA (Transcription termination-antitermination factor NusA); Participates in both transcription termination and antitermination.
  
  
 0.620
LCA_1840
Hypothetical cell surface protein precursor (with LPQTG sorting signal).
   
 
 0.604
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
  
 0.602
LCA_0630
Putative drug ABC exporter, membrane-spanning/permease subunit.
 
     0.595
pepX
X-Prolyl dipeptidyl-aminopeptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
  
   
 0.556
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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