node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LCA_0343 | LCA_0630 | LCA_0343 | LCA_0630 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Putative drug ABC exporter, membrane-spanning/permease subunit. | 0.720 |
LCA_0343 | LCA_1446 | LCA_0343 | LCA_1446 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 5 Proteins of unknown function that are similar to other proteins. | 0.464 |
LCA_0343 | mecA | LCA_0343 | LCA_1448 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.638 |
LCA_0343 | rpoE | LCA_0343 | LCA_1631 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.448 |
LCA_0630 | LCA_0343 | LCA_0630 | LCA_0343 | Putative drug ABC exporter, membrane-spanning/permease subunit. | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.720 |
LCA_0630 | LCA_1446 | LCA_0630 | LCA_1446 | Putative drug ABC exporter, membrane-spanning/permease subunit. | 5 Proteins of unknown function that are similar to other proteins. | 0.446 |
LCA_0630 | LCA_1447 | LCA_0630 | LCA_1447 | Putative drug ABC exporter, membrane-spanning/permease subunit. | 5 Proteins of unknown function that are similar to other proteins. | 0.528 |
LCA_0630 | mecA | LCA_0630 | LCA_1448 | Putative drug ABC exporter, membrane-spanning/permease subunit. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.673 |
LCA_0630 | rpoE | LCA_0630 | LCA_1631 | Putative drug ABC exporter, membrane-spanning/permease subunit. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.627 |
LCA_1446 | LCA_0343 | LCA_1446 | LCA_0343 | 5 Proteins of unknown function that are similar to other proteins. | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.464 |
LCA_1446 | LCA_0630 | LCA_1446 | LCA_0630 | 5 Proteins of unknown function that are similar to other proteins. | Putative drug ABC exporter, membrane-spanning/permease subunit. | 0.446 |
LCA_1446 | mecA | LCA_1446 | LCA_1448 | 5 Proteins of unknown function that are similar to other proteins. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.676 |
LCA_1446 | spxA | LCA_1446 | LCA_1449 | 5 Proteins of unknown function that are similar to other proteins. | Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.896 |
LCA_1447 | LCA_0630 | LCA_1447 | LCA_0630 | 5 Proteins of unknown function that are similar to other proteins. | Putative drug ABC exporter, membrane-spanning/permease subunit. | 0.528 |
LCA_1447 | mecA | LCA_1447 | LCA_1448 | 5 Proteins of unknown function that are similar to other proteins. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.863 |
LCA_1447 | spxA | LCA_1447 | LCA_1449 | 5 Proteins of unknown function that are similar to other proteins. | Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.593 |
LCA_1609 | mecA | LCA_1609 | LCA_1448 | 5 Proteins of unknown function that are similar to other proteins. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.652 |
LCA_1609 | rpoE | LCA_1609 | LCA_1631 | 5 Proteins of unknown function that are similar to other proteins. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.649 |
clpB | mecA | LCA_1040 | LCA_1448 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Similar to MecA, putative adapter protein for Clp protease; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.608 |
clpB | pbp2A | LCA_1040 | LCA_0621 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Bifunctional glycolsyltransferase/transpeptidase penicillin binding protein 2A. | 0.478 |