STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABS20403.1Protein of unknown function DUF972; Involved in initiation control of chromosome replication. Belongs to the YabA family. (116 aa)    
Predicted Functional Partners:
ABS20402.1
PFAM: PSP1 domain protein; KEGG: btl:BALH_0028 possible signal peptidase-like protein.
  
    0.815
ABS20401.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: bce:BC0037 DNA polymerase III, delta' subunit.
       0.769
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.764
ABS20378.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.685
ABS20399.1
PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: btl:BALH_0025 lysine decarboxylase.
  
    0.677
ABS20405.1
PFAM: Excinuclease ABC C subunit domain protein; KEGG: btl:BALH_0031 endo/excinuclease amino terminal domain.
 
    0.642
ABS21028.1
PFAM: ABC transporter EcsB; KEGG: btk:BT9727_0753 hypothetical protein.
  
     0.621
ABS20605.1
Putative transcriptional regulator, CopG family; KEGG: btl:BALH_0238 hypothetical protein.
  
     0.620
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.607
ABS20404.1
KEGG: btk:BT9727_0030 conserved hypothetical protein, possible methyltransferase.
  
  
 0.600
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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