node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABS20573.1 | ABS23401.1 | Bcer98_0206 | Bcer98_3178 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.992 |
ABS20573.1 | ABS23402.1 | Bcer98_0206 | Bcer98_3179 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.975 |
ABS20573.1 | hemA | Bcer98_0206 | Bcer98_3182 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.900 |
ABS20573.1 | hemC | Bcer98_0206 | Bcer98_3180 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
ABS20573.1 | hemL1 | Bcer98_0206 | Bcer98_0453 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bat:BAS0499 glutamate-1-semialdehyde-2,1-aminomutase. | 0.772 |
ABS20573.1 | hemL2 | Bcer98_0206 | Bcer98_3177 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4552 glutamate-1-semialdehyde aminotransferase. | 0.800 |
ABS20809.1 | hemL1 | Bcer98_0454 | Bcer98_0453 | ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: btl:BALH_0465 daunorubicin resistance, ATP-binding protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bat:BAS0499 glutamate-1-semialdehyde-2,1-aminomutase. | 0.593 |
ABS22058.1 | ABS23415.1 | Bcer98_1758 | Bcer98_3192 | TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bcz:BCZK2131 nonribosomal peptide synthetase. | PFAM: Acyl transferase; KEGG: pfl:PFL_2996 malonyl CoA-acyl carrier protein transacylase. | 0.976 |
ABS22058.1 | dltA | Bcer98_1758 | Bcer98_1092 | TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bcz:BCZK2131 nonribosomal peptide synthetase. | D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] | 0.890 |
ABS22058.1 | hemL1 | Bcer98_1758 | Bcer98_0453 | TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bcz:BCZK2131 nonribosomal peptide synthetase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bat:BAS0499 glutamate-1-semialdehyde-2,1-aminomutase. | 0.768 |
ABS22058.1 | hemL2 | Bcer98_1758 | Bcer98_3177 | TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bcz:BCZK2131 nonribosomal peptide synthetase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4552 glutamate-1-semialdehyde aminotransferase. | 0.781 |
ABS23401.1 | ABS20573.1 | Bcer98_3178 | Bcer98_0206 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | 0.992 |
ABS23401.1 | ABS23402.1 | Bcer98_3178 | Bcer98_3179 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.982 |
ABS23401.1 | hemA | Bcer98_3178 | Bcer98_3182 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.944 |
ABS23401.1 | hemC | Bcer98_3178 | Bcer98_3180 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
ABS23401.1 | hemL1 | Bcer98_3178 | Bcer98_0453 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bat:BAS0499 glutamate-1-semialdehyde-2,1-aminomutase. | 0.990 |
ABS23401.1 | hemL2 | Bcer98_3178 | Bcer98_3177 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4552 glutamate-1-semialdehyde aminotransferase. | 0.997 |
ABS23402.1 | ABS20573.1 | Bcer98_3179 | Bcer98_0206 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase. | 0.975 |
ABS23402.1 | ABS23401.1 | Bcer98_3179 | Bcer98_3178 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.982 |
ABS23402.1 | hemA | Bcer98_3179 | Bcer98_3182 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.958 |