STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
odhA2-oxoglutarate dehydrogenase, E1 subunit; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (958 aa)    
Predicted Functional Partners:
ABS21291.1
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
ABS22905.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: btl:BALH_3592 dihydrolipoamide dehydrogenase.
 
 0.994
ABS23090.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: btl:BALH_3773 dihydrolipoamide dehydrogenase.
 
 0.994
ABS23496.1
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: btk:BT9727_4322 isocitrate dehydrogenase.
   
 
 0.975
ABS23087.1
Catalytic domain of components of various dehydrogenase complexes; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bce:BC4157 dihydrolipoamide acetyltransferase.
 0.974
ABS22906.1
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: btl:BALH_3593 pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase.
 0.972
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 
 0.956
ABS21368.1
TIGRFAM: polyhydroxyalkanoic acid synthase, PhaR subunit; KEGG: btl:BALH_1178 PHA synthase subunit PhaR.
  
 0.933
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 0.931
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.928
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.