STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABPutative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (146 aa)    
Predicted Functional Partners:
ABS23006.1
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; Anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: btl:BALH_3692 anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.993
ABS23004.1
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.984
ABS22788.1
Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
  
  
 0.866
ABS22841.1
RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; KEGG: bat:BAS3823 prophage LambdaBa02, RNA polymerase sigma-F factor, putative.
 
 
 0.865
ABS22786.1
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.848
ABS23000.1
TIGRFAM: Sporulation stage V protein AC; PFAM: SpoVA protein; KEGG: bcz:BCZK3825 stage V sporulation protein AC.
 
   
 0.843
ABS22999.1
PFAM: Stage V sporulation AD family protein; KEGG: bcz:BCZK3824 stage V sporulation protein AD.
 
    0.838
ABS22998.1
TIGRFAM: Sporulation stage V protein AE; PFAM: SpoVA protein; KEGG: btl:BALH_3683 stage V sporulation protein AE, N-terminal region.
 
     0.837
ABS21554.1
Sporulation stage IV protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.822
ABS23989.1
TIGRFAM: Sporulation stage III transcriptional regulator SpoIIID; KEGG: btl:BALH_4786 stage III sporulation protein D.
  
   
 0.813
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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