STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (444 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.996
hemL2
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4552 glutamate-1-semialdehyde aminotransferase.
 
 0.994
hemL1
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bat:BAS0499 glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.985
ABS23402.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.958
ABS23401.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcz:BCZK4206 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.944
ABS20573.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: btl:BALH_1905 uroporphiryn-III C-methyltransferase.
 
  
 0.900
ABS23404.1
PFAM: cytochrome c assembly protein; KEGG: btl:BALH_4058 HemX protein.
  
  
 0.893
ABS21473.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bce:BC1426 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.767
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.578
ABS21475.1
TIGRFAM: siroheme synthase; KEGG: btl:BALH_1283 siroheme synthase (precorrin-2 oxidase).
 
   
 0.530
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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