node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABS22115.1 | ABS23211.1 | Bcer98_1818 | Bcer98_2984 | PFAM: purine or other phosphorylase family 1; KEGG: bce:BC2503 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | 0.447 |
ABS22115.1 | luxS | Bcer98_1818 | Bcer98_3461 | PFAM: purine or other phosphorylase family 1; KEGG: bce:BC2503 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.971 |
ABS22115.1 | mtnN | Bcer98_1818 | Bcer98_3086 | PFAM: purine or other phosphorylase family 1; KEGG: bce:BC2503 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.927 |
ABS23210.1 | ABS23211.1 | Bcer98_2983 | Bcer98_2984 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | 0.999 |
ABS23210.1 | ABS23212.1 | Bcer98_2983 | Bcer98_2985 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: bcz:BCZK4007 cystathionine beta-lyase. | 0.971 |
ABS23210.1 | ABS23213.1 | Bcer98_2983 | Bcer98_2986 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bat:BAS4159 cystathionine beta-lyase. | 0.971 |
ABS23210.1 | ABS23308.1 | Bcer98_2983 | Bcer98_3084 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: bce:BC4366 cystathionine beta-lyase. | 0.942 |
ABS23210.1 | ABS23309.1 | Bcer98_2983 | Bcer98_3085 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bca:BCE_4455 O-acetylserine lyase. | 0.941 |
ABS23210.1 | ABS24109.1 | Bcer98_2983 | Bcer98_3925 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: baa:BA_0514 Cys/Met metabolism PLP-dependent enzyme. | 0.949 |
ABS23210.1 | luxS | Bcer98_2983 | Bcer98_3461 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.947 |
ABS23210.1 | metE | Bcer98_2983 | Bcer98_2704 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.982 |
ABS23211.1 | ABS22115.1 | Bcer98_2984 | Bcer98_1818 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | PFAM: purine or other phosphorylase family 1; KEGG: bce:BC2503 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. | 0.447 |
ABS23211.1 | ABS23210.1 | Bcer98_2984 | Bcer98_2983 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
ABS23211.1 | ABS23212.1 | Bcer98_2984 | Bcer98_2985 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: bcz:BCZK4007 cystathionine beta-lyase. | 0.993 |
ABS23211.1 | ABS23213.1 | Bcer98_2984 | Bcer98_2986 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bat:BAS4159 cystathionine beta-lyase. | 0.992 |
ABS23211.1 | ABS23308.1 | Bcer98_2984 | Bcer98_3084 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: bce:BC4366 cystathionine beta-lyase. | 0.983 |
ABS23211.1 | ABS23309.1 | Bcer98_2984 | Bcer98_3085 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bca:BCE_4455 O-acetylserine lyase. | 0.944 |
ABS23211.1 | ABS24109.1 | Bcer98_2984 | Bcer98_3925 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: baa:BA_0514 Cys/Met metabolism PLP-dependent enzyme. | 0.947 |
ABS23211.1 | luxS | Bcer98_2984 | Bcer98_3461 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.947 |
ABS23211.1 | metE | Bcer98_2984 | Bcer98_2704 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: btl:BALH_3851 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.999 |