STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPUM_0447Phosphoserine phosphatase. (199 aa)    
Predicted Functional Partners:
BPUM_0442
Serine/threonine protein kinase.
 
 0.982
BPUM_3280
Biphenyl 2,3-dioxygenase.
 
 0.982
BPUM_2671
Biphenyl 2,3-dioxygenase.
 
 0.980
BPUM_0355
Histidine kinase.
 
 0.978
BPUM_0441
RsbT antagonist protein RsbS.
 
 0.978
BPUM_0440
RsbT co-antagonist protein RsbRA.
 
 0.975
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 0.963
BPUM_0446
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase.
 
  
 0.962
BPUM_0444
Anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
  
 0.942
BPUM_1683
RsbT co-antagonist protein RsbRB.
 
 0.933
Your Current Organism:
Bacillus pumilus
NCBI taxonomy Id: 315750
Other names: B. pumilus SAFR-032, Bacillus pumilus SAFR-032, Bacillus pumilus str. SAFR-032, Bacillus pumilus strain SAFR-032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.