node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
birA | murB | BPUM_1975 | BPUM_1416 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.771 |
ddl | divIB | BPUM_0427 | BPUM_1417 | D-alanine--D-alanine ligase; Cell wall formation. | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.833 |
ddl | mraY | BPUM_0427 | BPUM_1412 | D-alanine--D-alanine ligase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.714 |
ddl | murA | BPUM_0427 | BPUM_3321 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.769 |
ddl | murA-2 | BPUM_0427 | BPUM_3354 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.775 |
ddl | murB | BPUM_0427 | BPUM_1416 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.989 |
ddl | murC | BPUM_0427 | BPUM_2626 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.993 |
ddl | murD | BPUM_0427 | BPUM_1413 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.902 |
ddl | murF | BPUM_0427 | BPUM_0428 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.994 |
ddl | murG | BPUM_0427 | BPUM_1415 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.868 |
divIB | ddl | BPUM_1417 | BPUM_0427 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.833 |
divIB | mraY | BPUM_1417 | BPUM_1412 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.582 |
divIB | murB | BPUM_1417 | BPUM_1416 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.850 |
divIB | murC | BPUM_1417 | BPUM_2626 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | UDP-N-acetylmuramate--alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.883 |
divIB | murD | BPUM_1417 | BPUM_1413 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.859 |
divIB | murF | BPUM_1417 | BPUM_0428 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.915 |
divIB | murG | BPUM_1417 | BPUM_1415 | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.885 |
mraY | ddl | BPUM_1412 | BPUM_0427 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.714 |
mraY | divIB | BPUM_1412 | BPUM_1417 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Dihydropteridine reductase; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.582 |
mraY | murA | BPUM_1412 | BPUM_3321 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.824 |