node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPUM_1357 | BPUM_1814 | BPUM_1357 | BPUM_1814 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Glutamate synthase. | 0.830 |
BPUM_1357 | BPUM_2561 | BPUM_1357 | BPUM_2561 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 0.782 |
BPUM_1357 | mdh | BPUM_1357 | BPUM_2554 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.414 |
BPUM_1357 | pckA | BPUM_1357 | BPUM_2687 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.795 |
BPUM_1357 | sucC | BPUM_1357 | BPUM_1507 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.907 |
BPUM_1357 | sucD | BPUM_1357 | BPUM_1508 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.886 |
BPUM_1814 | BPUM_1357 | BPUM_1814 | BPUM_1357 | Glutamate synthase. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.830 |
BPUM_1814 | BPUM_2547 | BPUM_1814 | BPUM_2547 | Glutamate synthase. | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.818 |
BPUM_1814 | BPUM_2561 | BPUM_1814 | BPUM_2561 | Glutamate synthase. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 0.675 |
BPUM_1814 | eno | BPUM_1814 | BPUM_3053 | Glutamate synthase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.902 |
BPUM_1814 | mdh | BPUM_1814 | BPUM_2554 | Glutamate synthase. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.902 |
BPUM_1814 | pckA | BPUM_1814 | BPUM_2687 | Glutamate synthase. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.941 |
BPUM_1814 | sucC | BPUM_1814 | BPUM_1507 | Glutamate synthase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.951 |
BPUM_1814 | sucD | BPUM_1814 | BPUM_1508 | Glutamate synthase. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.955 |
BPUM_2547 | BPUM_1814 | BPUM_2547 | BPUM_1814 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glutamate synthase. | 0.818 |
BPUM_2547 | BPUM_2561 | BPUM_2547 | BPUM_2561 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 0.932 |
BPUM_2547 | eno | BPUM_2547 | BPUM_3053 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.956 |
BPUM_2547 | mdh | BPUM_2547 | BPUM_2554 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.759 |
BPUM_2547 | pckA | BPUM_2547 | BPUM_2687 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.738 |
BPUM_2561 | BPUM_1357 | BPUM_2561 | BPUM_1357 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.782 |