node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_0635 | RPE_0683 | RPE_0635 | RPE_0683 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | 0.868 |
RPE_0635 | RPE_3057 | RPE_0635 | RPE_3057 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.937 |
RPE_0635 | RPE_3438 | RPE_0635 | RPE_3438 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 2,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | 0.936 |
RPE_0635 | RPE_4110 | RPE_0635 | RPE_4110 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate kinase; KEGG: rpa:RPA4193 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.937 |
RPE_0635 | RPE_4405 | RPE_0635 | RPE_4405 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | KEGG: rpc:RPC_4343 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. | 0.936 |
RPE_0635 | mdh | RPE_0635 | RPE_0300 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.947 |
RPE_0635 | pckA | RPE_0635 | RPE_0819 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.931 |
RPE_0635 | ppc | RPE_0635 | RPE_1791 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.927 |
RPE_0683 | RPE_0635 | RPE_0683 | RPE_0635 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.868 |
RPE_0683 | RPE_3057 | RPE_0683 | RPE_3057 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.710 |
RPE_0683 | RPE_4110 | RPE_0683 | RPE_4110 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | PFAM: pyruvate kinase; KEGG: rpa:RPA4193 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.710 |
RPE_0683 | RPE_4405 | RPE_0683 | RPE_4405 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | KEGG: rpc:RPC_4343 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. | 0.601 |
RPE_0683 | eno | RPE_0683 | RPE_2607 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.964 |
RPE_0683 | mdh | RPE_0683 | RPE_0300 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.914 |
RPE_0683 | pckA | RPE_0683 | RPE_0819 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.870 |
RPE_0683 | pgk | RPE_0683 | RPE_4725 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | PFAM: phosphoglycerate kinase; KEGG: rpc:RPC_4770 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.474 |
RPE_0683 | ppc | RPE_0683 | RPE_1791 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.922 |
RPE_3057 | RPE_0635 | RPE_3057 | RPE_0635 | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.937 |
RPE_3057 | RPE_0683 | RPE_3057 | RPE_0683 | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | 0.710 |
RPE_3057 | RPE_3438 | RPE_3057 | RPE_3438 | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | 2,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | 0.917 |