node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_0915 | RPE_1359 | RPE_0915 | RPE_1359 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | 0.657 |
RPE_0915 | RPE_3400 | RPE_0915 | RPE_3400 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | 0.662 |
RPE_0915 | RPE_4787 | RPE_0915 | RPE_4787 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.658 |
RPE_0915 | bioB | RPE_0915 | RPE_2208 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.864 |
RPE_0915 | bioD | RPE_0915 | RPE_3401 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.909 |
RPE_1359 | RPE_0915 | RPE_1359 | RPE_0915 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.657 |
RPE_1359 | RPE_3402 | RPE_1359 | RPE_3402 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.758 |
RPE_1359 | RPE_4787 | RPE_1359 | RPE_4787 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.902 |
RPE_1359 | bioB | RPE_1359 | RPE_2208 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.816 |
RPE_1359 | bioD | RPE_1359 | RPE_3401 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.918 |
RPE_2207 | bioB | RPE_2207 | RPE_2208 | Transcriptional regulator/antitoxin, MazE; PFAM: SpoVT/AbrB domain protein; KEGG: nmu:Nmul_A0985 transcriptional regulator/antitoxin, MazE. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.618 |
RPE_2537 | bioB | RPE_2537 | RPE_2208 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: rpc:RPC_2418 biotin--acetyl-CoA-carboxylase ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.932 |
RPE_2537 | bioD | RPE_2537 | RPE_3401 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: rpc:RPC_2418 biotin--acetyl-CoA-carboxylase ligase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.428 |
RPE_3400 | RPE_0915 | RPE_3400 | RPE_0915 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.662 |
RPE_3400 | RPE_3402 | RPE_3400 | RPE_3402 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.998 |
RPE_3400 | bioB | RPE_3400 | RPE_2208 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.925 |
RPE_3400 | bioD | RPE_3400 | RPE_3401 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.996 |
RPE_3402 | RPE_1359 | RPE_3402 | RPE_1359 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | 0.758 |
RPE_3402 | RPE_3400 | RPE_3402 | RPE_3400 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | 0.998 |
RPE_3402 | RPE_4787 | RPE_3402 | RPE_4787 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.761 |