node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_0398 | dnaA | RPE_0398 | RPE_0001 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.671 |
RPE_0398 | mfd | RPE_0398 | RPE_2790 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.598 |
RPE_0398 | recR | RPE_0398 | RPE_4811 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.558 |
RPE_0398 | ruvA | RPE_0398 | RPE_4769 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.682 |
RPE_0398 | ruvB | RPE_0398 | RPE_4767 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.635 |
RPE_0398 | ruvC | RPE_0398 | RPE_4770 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.467 |
RPE_4768 | RPE_4771 | RPE_4768 | RPE_4771 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | 0.442 |
RPE_4768 | ruvA | RPE_4768 | RPE_4769 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.875 |
RPE_4768 | ruvB | RPE_4768 | RPE_4767 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.566 |
RPE_4768 | ruvC | RPE_4768 | RPE_4770 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.627 |
RPE_4771 | RPE_4768 | RPE_4771 | RPE_4768 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | 0.442 |
RPE_4771 | dnaA | RPE_4771 | RPE_0001 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.420 |
RPE_4771 | pheT | RPE_4771 | RPE_0493 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rpc:RPC_0444 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.564 |
RPE_4771 | ruvA | RPE_4771 | RPE_4769 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.710 |
RPE_4771 | ruvB | RPE_4771 | RPE_4767 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.770 |
RPE_4771 | ruvC | RPE_4771 | RPE_4770 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.774 |
dnaA | RPE_0398 | RPE_0001 | RPE_0398 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rpc:RPC_0276 cell divisionFtsK/SpoIIIE. | 0.671 |
dnaA | RPE_4771 | RPE_0001 | RPE_4771 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | 0.420 |
dnaA | mfd | RPE_0001 | RPE_2790 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.476 |
dnaA | pheT | RPE_0001 | RPE_0493 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rpc:RPC_0444 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.444 |