node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_0360 | ruvC | RPE_0360 | RPE_4770 | Mg chelatase, subunit ChlI; KEGG: rpc:RPC_0317 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.746 |
RPE_2671 | RPE_4771 | RPE_2671 | RPE_4771 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | 0.426 |
RPE_2671 | polA | RPE_2671 | RPE_4821 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.767 |
RPE_2671 | recA | RPE_2671 | RPE_1594 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.599 |
RPE_2671 | ruvC | RPE_2671 | RPE_4770 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.515 |
RPE_4768 | RPE_4771 | RPE_4768 | RPE_4771 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | 0.442 |
RPE_4768 | polA | RPE_4768 | RPE_4821 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.429 |
RPE_4768 | ruvA | RPE_4768 | RPE_4769 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.875 |
RPE_4768 | ruvB | RPE_4768 | RPE_4767 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.566 |
RPE_4768 | ruvC | RPE_4768 | RPE_4770 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.627 |
RPE_4771 | RPE_2671 | RPE_4771 | RPE_2671 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | 0.426 |
RPE_4771 | RPE_4768 | RPE_4771 | RPE_4768 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rpa:RPA1101 cytidine deaminase. | 0.442 |
RPE_4771 | polA | RPE_4771 | RPE_4821 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.425 |
RPE_4771 | ruvA | RPE_4771 | RPE_4769 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.710 |
RPE_4771 | ruvB | RPE_4771 | RPE_4767 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.770 |
RPE_4771 | ruvC | RPE_4771 | RPE_4770 | PFAM: protein of unknown function DUF28; KEGG: rpc:RPC_4807 protein of unknown function DUF28. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.774 |
def | polA | RPE_0656 | RPE_4821 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.570 |
def | recA | RPE_0656 | RPE_1594 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.488 |
def | ruvC | RPE_0656 | RPE_4770 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.633 |
polA | RPE_2671 | RPE_4821 | RPE_2671 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein. | 0.767 |