node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPC_0056 | apt | RPC_0056 | RPC_4387 | Glutamine amidotransferase class-I. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.935 |
RPC_0056 | guaA | RPC_0056 | RPC_3063 | Glutamine amidotransferase class-I. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.919 |
RPC_0056 | guaB | RPC_0056 | RPC_3071 | Glutamine amidotransferase class-I. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.988 |
RPC_0056 | purA | RPC_0056 | RPC_4086 | Glutamine amidotransferase class-I. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.532 |
RPC_0056 | pyrH | RPC_0056 | RPC_2438 | Glutamine amidotransferase class-I. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.471 |
RPC_0056 | surE | RPC_0056 | RPC_2519 | Glutamine amidotransferase class-I. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.925 |
RPC_1610 | apt | RPC_1610 | RPC_4387 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.952 |
RPC_1610 | guaA | RPC_1610 | RPC_3063 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.936 |
RPC_1610 | guaB | RPC_1610 | RPC_3071 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.893 |
RPC_1610 | purA | RPC_1610 | RPC_4086 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
RPC_1610 | pyrF | RPC_1610 | RPC_0333 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.632 |
RPC_1610 | pyrH | RPC_1610 | RPC_2438 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.459 |
RPC_1610 | surE | RPC_1610 | RPC_2519 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.930 |
RPC_4089 | guaA | RPC_4089 | RPC_3063 | Pyrimidine nucleoside phosphorylase-like. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.458 |
RPC_4089 | guaB | RPC_4089 | RPC_3071 | Pyrimidine nucleoside phosphorylase-like. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.452 |
RPC_4089 | surE | RPC_4089 | RPC_2519 | Pyrimidine nucleoside phosphorylase-like. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.926 |
apt | RPC_0056 | RPC_4387 | RPC_0056 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine amidotransferase class-I. | 0.935 |
apt | RPC_1610 | RPC_4387 | RPC_1610 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.952 |
apt | guaA | RPC_4387 | RPC_3063 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.992 |
apt | guaB | RPC_4387 | RPC_3071 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.471 |