STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)    
Predicted Functional Partners:
RPB_0908
Maleylacetoacetate isomerase.
 
 
 0.988
RPB_0909
Fumarylacetoacetate hydrolase.
 
  
 0.983
RPB_1495
Protein of unknown function DUF1446.
  
 
 0.913
RPB_0906
Beta-lactamase-like.
 
  
 0.874
RPB_0903
3-(3-hydroxy-phenyl)propionate hydroxylase.
 
  
 0.826
RPB_0904
Conserved hypothetical protein.
 
     0.756
RPB_0099
Pterin-4-alpha-carbinolamine dehydratase.
 
  
 0.717
RPB_1595
Fumarylacetoacetate (FAA) hydrolase.
  
  
 0.669
RPB_1704
5-carboxymethyl-2-hydroxymuconate delta-isomerase.
  
  
 0.613
RPB_3432
Fumarylacetoacetate (FAA) hydrolase.
  
  
 0.613
Your Current Organism:
Rhodopseudomonas palustris HaA2
NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2
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