node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPB_0002 | RPB_1876 | RPB_0002 | RPB_1876 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP dependent DNA ligase, central. | 0.963 |
RPB_0002 | RPB_2532 | RPB_0002 | RPB_2532 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Helicase-like. | 0.653 |
RPB_0002 | RPB_2898 | RPB_0002 | RPB_2898 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.769 |
RPB_0002 | RPB_4616 | RPB_0002 | RPB_4616 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein. | 0.407 |
RPB_0002 | polA | RPB_0002 | RPB_0848 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.994 |
RPB_0002 | rpoA | RPB_0002 | RPB_2319 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.646 |
RPB_1599 | RPB_1876 | RPB_1599 | RPB_1876 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | ATP dependent DNA ligase, central. | 0.746 |
RPB_1876 | RPB_0002 | RPB_1876 | RPB_0002 | ATP dependent DNA ligase, central. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.963 |
RPB_1876 | RPB_1599 | RPB_1876 | RPB_1599 | ATP dependent DNA ligase, central. | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | 0.746 |
RPB_1876 | RPB_2532 | RPB_1876 | RPB_2532 | ATP dependent DNA ligase, central. | Helicase-like. | 0.685 |
RPB_1876 | RPB_2898 | RPB_1876 | RPB_2898 | ATP dependent DNA ligase, central. | Exodeoxyribonuclease III. | 0.708 |
RPB_1876 | RPB_3659 | RPB_1876 | RPB_3659 | ATP dependent DNA ligase, central. | Protein of unknown function DUF72. | 0.746 |
RPB_1876 | RPB_4616 | RPB_1876 | RPB_4616 | ATP dependent DNA ligase, central. | Conserved hypothetical protein. | 0.775 |
RPB_1876 | ku | RPB_1876 | RPB_0698 | ATP dependent DNA ligase, central. | Ku-like protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.947 |
RPB_1876 | ku-2 | RPB_1876 | RPB_1875 | ATP dependent DNA ligase, central. | Ku-like protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.974 |
RPB_1876 | polA | RPB_1876 | RPB_0848 | ATP dependent DNA ligase, central. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.962 |
RPB_1876 | rpoA | RPB_1876 | RPB_2319 | ATP dependent DNA ligase, central. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.715 |
RPB_2532 | RPB_0002 | RPB_2532 | RPB_0002 | Helicase-like. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.653 |
RPB_2532 | RPB_1876 | RPB_2532 | RPB_1876 | Helicase-like. | ATP dependent DNA ligase, central. | 0.685 |
RPB_2532 | polA | RPB_2532 | RPB_0848 | Helicase-like. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.964 |