node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPB_0112 | apt | RPB_0112 | RPB_4317 | Glutamine amidotransferase class-I. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.945 |
RPB_0112 | gmk | RPB_0112 | RPB_2472 | Glutamine amidotransferase class-I. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
RPB_0112 | guaA | RPB_0112 | RPB_3189 | Glutamine amidotransferase class-I. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.920 |
RPB_0112 | guaC | RPB_0112 | RPB_0217 | Glutamine amidotransferase class-I. | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.964 |
RPB_1423 | RPB_1802 | RPB_1423 | RPB_1802 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Metal dependent phosphohydrolase. | 0.905 |
RPB_1423 | RPB_2608 | RPB_1423 | RPB_2608 | Pyruvate kinase; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.921 |
RPB_1423 | eno | RPB_1423 | RPB_2778 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.991 |
RPB_1423 | gmk | RPB_1423 | RPB_2472 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.931 |
RPB_1423 | guaA | RPB_1423 | RPB_3189 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.530 |
RPB_1423 | ndk | RPB_1423 | RPB_2485 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.910 |
RPB_1802 | RPB_1423 | RPB_1802 | RPB_1423 | Metal dependent phosphohydrolase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.905 |
RPB_1802 | RPB_2608 | RPB_1802 | RPB_2608 | Metal dependent phosphohydrolase. | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
RPB_1802 | gmk | RPB_1802 | RPB_2472 | Metal dependent phosphohydrolase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
RPB_1802 | ndk | RPB_1802 | RPB_2485 | Metal dependent phosphohydrolase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.917 |
RPB_2471 | gmk | RPB_2471 | RPB_2472 | Conserved hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.965 |
RPB_2608 | RPB_1423 | RPB_2608 | RPB_1423 | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.921 |
RPB_2608 | RPB_1802 | RPB_2608 | RPB_1802 | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Metal dependent phosphohydrolase. | 0.918 |
RPB_2608 | gmk | RPB_2608 | RPB_2472 | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
RPB_2608 | ndk | RPB_2608 | RPB_2485 | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.928 |
apt | RPB_0112 | RPB_4317 | RPB_0112 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine amidotransferase class-I. | 0.945 |