STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (524 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.994
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.994
RPB_3247
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.981
ilvD
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.979
RPB_2095
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.974
RPB_4175
Branched chain amino acid aminotransferase.
  
 0.966
RPB_0999
Aminotransferase, class IV.
  
 0.965
RPB_3345
Acetolactate synthase, large subunit.
 
 
 0.955
RPB_0851
Pyruvate flavodoxin/ferredoxin oxidoreductase.
  
 
 0.949
RPB_3344
Acetolactate synthase, small subunit.
 
 
 0.945
Your Current Organism:
Rhodopseudomonas palustris HaA2
NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2
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