node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Geob_2682 | pyrF | Geob_2682 | Geob_2402 | HAD superfamily hydrolase. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.902 |
Geob_2682 | pyrH | Geob_2682 | Geob_1520 | HAD superfamily hydrolase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
Geob_2682 | pyrR | Geob_2682 | Geob_3263 | HAD superfamily hydrolase. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.900 |
Geob_2682 | surE | Geob_2682 | Geob_3335 | HAD superfamily hydrolase. | Nucleoside-3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
carA | carB | Geob_3266 | Geob_3271 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |
carA | pyrB | Geob_3266 | Geob_3264 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Geob_3266 | Geob_3265 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |
carA | pyrD | Geob_3266 | Geob_2780 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.961 |
carA | pyrE | Geob_3266 | Geob_2889 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.946 |
carA | pyrF | Geob_3266 | Geob_2402 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.946 |
carA | pyrR | Geob_3266 | Geob_3263 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.911 |
carB | carA | Geob_3271 | Geob_3266 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
carB | pyrB | Geob_3271 | Geob_3264 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | Geob_3271 | Geob_3265 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carB | pyrD | Geob_3271 | Geob_2780 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.961 |
carB | pyrE | Geob_3271 | Geob_2889 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.953 |
carB | pyrF | Geob_3271 | Geob_2402 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.955 |
carB | pyrR | Geob_3271 | Geob_3263 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.911 |
pyrB | carA | Geob_3264 | Geob_3266 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
pyrB | carB | Geob_3264 | Geob_3271 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |