STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lexATranscriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (214 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.989
Haur_1402
SMART: AAA ATPase; KEGG: nfa:nfa14870 hypothetical protein.
  
 
 0.904
Haur_3426
KEGG: rca:Rcas_3401 hypothetical protein.
  
 
 0.904
Haur_3043
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mag:amb3988 modification methylase CcrmI; Belongs to the N(4)/N(6)-methyltransferase family.
    
 0.842
Haur_2756
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hch:HCH_02488 BamHI-like site-specific methyltransferase.
    
 0.822
Haur_3320
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.764
Haur_0318
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: swo:Swol_0838 site-specific DNA-methyltransferase (adenine-specific).
    
 0.695
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
 
  
 0.654
Haur_1513
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
  
 0.549
Haur_4064
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rca:Rcas_1080 site-specific DNA-methyltransferase (adenine-specific); Belongs to the N(4)/N(6)-methyltransferase family.
    
 0.499
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
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