node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Haur_2997 | Haur_2998 | Haur_2997 | Haur_2998 | PFAM: response regulator receiver; KEGG: syn:slr1982 two-component response regulator (CheY subfamily). | PFAM: conserved hypothetical protein; KEGG: rca:Rcas_4073 SAM-dependent methyltransferase. | 0.752 |
Haur_2997 | lon2 | Haur_2997 | Haur_2996 | PFAM: response regulator receiver; KEGG: syn:slr1982 two-component response regulator (CheY subfamily). | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.504 |
Haur_2998 | Haur_2997 | Haur_2998 | Haur_2997 | PFAM: conserved hypothetical protein; KEGG: rca:Rcas_4073 SAM-dependent methyltransferase. | PFAM: response regulator receiver; KEGG: syn:slr1982 two-component response regulator (CheY subfamily). | 0.752 |
Haur_2998 | lon2 | Haur_2998 | Haur_2996 | PFAM: conserved hypothetical protein; KEGG: rca:Rcas_4073 SAM-dependent methyltransferase. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.502 |
Haur_3991 | Haur_4376 | Haur_3991 | Haur_4376 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | 0.556 |
Haur_3991 | Haur_4377 | Haur_3991 | Haur_4377 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | PFAM: ATP-binding region ATPase domain protein; KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | 0.556 |
Haur_3991 | clpP | Haur_3991 | Haur_3828 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.946 |
Haur_3991 | clpX | Haur_3991 | Haur_3829 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.458 |
Haur_3991 | groL | Haur_3991 | Haur_3679 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.667 |
Haur_3991 | grpE | Haur_3991 | Haur_0439 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.801 |
Haur_3991 | htpG | Haur_3991 | Haur_0322 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.556 |
Haur_3991 | lon2 | Haur_3991 | Haur_2996 | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.557 |
Haur_4376 | Haur_3991 | Haur_4376 | Haur_3991 | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | 0.556 |
Haur_4376 | Haur_4377 | Haur_4376 | Haur_4377 | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | PFAM: ATP-binding region ATPase domain protein; KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | 0.819 |
Haur_4376 | groL | Haur_4376 | Haur_3679 | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.814 |
Haur_4376 | grpE | Haur_4376 | Haur_0439 | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.709 |
Haur_4376 | lon2 | Haur_4376 | Haur_2996 | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.506 |
Haur_4377 | Haur_3991 | Haur_4377 | Haur_3991 | PFAM: ATP-binding region ATPase domain protein; KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_1484 ClpA/B family protein. | 0.556 |
Haur_4377 | Haur_4376 | Haur_4377 | Haur_4376 | PFAM: ATP-binding region ATPase domain protein; KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | 0.819 |
Haur_4377 | groL | Haur_4377 | Haur_3679 | PFAM: ATP-binding region ATPase domain protein; KEGG: hch:HCH_01594 molecular chaperone, HSP90 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.814 |