node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Haur_1887 | Haur_3304 | Haur_1887 | Haur_3304 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: xom:XOO_2745 valine-pyruvate aminotransferase. | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | 0.905 |
Haur_3301 | Haur_3303 | Haur_3301 | Haur_3303 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 0.989 |
Haur_3301 | Haur_3304 | Haur_3301 | Haur_3304 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | 0.826 |
Haur_3301 | Haur_4448 | Haur_3301 | Haur_4448 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: rca:Rcas_1556 acetolactate synthase, small subunit. | 0.603 |
Haur_3301 | ilvC | Haur_3301 | Haur_4447 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.774 |
Haur_3301 | ilvD | Haur_3301 | Haur_4450 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: sth:STH2685 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.789 |
Haur_3301 | leuC | Haur_3301 | Haur_3302 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.988 |
Haur_3301 | leuC-2 | Haur_3301 | Haur_4441 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.836 |
Haur_3301 | leuD | Haur_3301 | Haur_4440 | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.845 |
Haur_3303 | Haur_3301 | Haur_3303 | Haur_3301 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.989 |
Haur_3303 | Haur_3304 | Haur_3303 | Haur_3304 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | 0.997 |
Haur_3303 | Haur_4448 | Haur_3303 | Haur_4448 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: rca:Rcas_1556 acetolactate synthase, small subunit. | 0.862 |
Haur_3303 | ilvC | Haur_3303 | Haur_4447 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.920 |
Haur_3303 | ilvD | Haur_3303 | Haur_4450 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | KEGG: sth:STH2685 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.885 |
Haur_3303 | leuC | Haur_3303 | Haur_3302 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
Haur_3303 | leuC-2 | Haur_3303 | Haur_4441 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.941 |
Haur_3303 | leuD | Haur_3303 | Haur_4440 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.573 |
Haur_3304 | Haur_1887 | Haur_3304 | Haur_1887 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: xom:XOO_2745 valine-pyruvate aminotransferase. | 0.905 |
Haur_3304 | Haur_3301 | Haur_3304 | Haur_3301 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | PFAM: pyruvate carboxyltransferase; KEGG: cne:CND01200 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.826 |
Haur_3304 | Haur_3303 | Haur_3304 | Haur_3303 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rca:Rcas_3471 3-isopropylmalate dehydrogenase. | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: rca:Rcas_3472 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 0.997 |